Rashmi Desai began her acting career in the early 2000s, making her debut with the Gujarati serial "Kshatriya Kanya." However, it was her role as Aarti in the popular sitcom "Tu Tu Main Main" (2000-2003) that brought her to the limelight. Her on-screen chemistry with co-star Sachin Khot was well-received, and the show's success marked the beginning of her successful career.